Magic mushrooms have recently sparked curiosity for their potential benefits in managing mental health disorders, particularly depression. A growing trend involves regular consumption of around 25 mg of the active ingredient, available for purchase at a mushroom dispensary. This dosage has shown promising results, providing relief and potentially complementing conventional depression treatments.
A study conducted by a group of researchers indicates that psilocybin, the active component in magic mushrooms, has demonstrated positive results in treating depression.
Key Insights:
- Depression symptoms can improve within just eight days with the use of Psilocybin.
- The side effects of Psilocybin are generally mild to moderate and well-tolerated.
- A dose of 25mg of Psilocybin can lead to altered perception, mood changes, increased creativity, and a sense of unity.

One Dose Could Be Sufficient
A recent study used a rigorous methodology, implementing a randomized, multi-blinded design to compare a single dose of psilocybin with an active placebo (niacin). The research evaluated the onset, duration of benefits, and safety profile of psilocybin over a six-week timeframe.
Study Participants
The study targeted individuals aged 21 to 65, who met the criteria for Major Depressive Disorder (MDD) as defined in the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) and were going through a depressive episode lasting at least 60 days at that point.
Study Procedure
Participants received either a single 25-mg oral dose of psilocybin or a 100-mg dose of niacin. Niacin served as an active placebo, inducing an immediate physiological response (flushing) to maintain the study’s blinding integrity.
Both the psilocybin and the niacin placebo were provided following a standard “set and setting” procedure. The preparation sessions, guided by two facilitators, lasted between 6 and
The dosing session typically lasted between 7 to 10 hours in a relaxing environment. Participants were urged to contemplate their experiences four hours after the dosage.
Insights from the Study
Evidence of depression reduction was observed as soon as eight days after the administration of psilocybin. This promising effect remained consistent throughout the six-week follow-up period. It showed increased response and remission rates according to the Montgomery-Asberg Depression Rating Scale (MADRS), compared to other psilocybin studies and Treatment-Resistant Depression.
Psilocybin outperformed niacin in terms of psychosocial functioning. Psilocybin usage showed promise in several aspects, including reducing disease severity, lowering anxiety, decreasing self-reported depressive symptoms, and improving life quality.
The majority of participants tolerated the compound well, experiencing only minor or moderate side effects, mostly during the initial dose. However, psilocybin treatment had more frequent and severe side effects than niacin, which is consistent with our current understanding of its effects.
The researchers highlighted that psychedelics like psilocybin might produce side effects not always detected by standard rating scales or could reveal previously undiagnosed psychiatric conditions while effectively treating specific syndromes.
What Does a 25-mg Dose Entail?
A standard psychedelic dose typically consists of 15 to 25 milligrams of psilocybin (1.5 to 2.5 grams of dried mushrooms). This is the usual dosage for individuals seeking the full psychedelic effects of magic mushrooms.
This dosage can result in altered perception, mood shifts, enhanced creativity, and a feeling of unity with the environment. While minor visual effects might be experienced, intense hallucinations are rare. It is akin to entering a vivid dreamworld where reality effortlessly fuses with a captivating mix of visual and auditory sensations.
The euphoric feelings often express themselves through dance, gentle movements, or simply yielding to the psychedelic rhythm. The experience typically lasts between 4 to 8 hours. At this level, visual distortions may become more prominent. Patterns seem to animate and morph, and your surroundings appear to pulsate with energy.
This dosage can be controlled, but it necessitates a regulated setting and a positive mindset. It offers a journey filled with awe and wonder, encouraging you to delve into consciousness. with eager caution.
- An enhanced perception of color.
- Vision alterations, such as seeing objects “breathe” or shift.
- The occurrence of synesthesia, for example, “seeing sounds” or “hearing colors”.
- Obtaining a deep appreciation for music.
- Sudden bouts of laughter.
- Changes in the sense of touch.
- Engagement in introspection.
- Feelings of euphoria.
- Changes in the perception of time.
- An increase in heart rate and blood pressure.
Available Products at Magic Mushroom Stores
Magic mushroom stores offer a variety of products infused with psilocybin. The assortment includes dried mushrooms, edibles, capsules, and beverages, among others. Dried mushrooms are particularly favored.
Over 200 types of magic mushrooms are recognized by Health Canada, with Psilocybe cubensis being a commonly sold strain. This species comes in several variants, providing a broad selection similar to what you’d find at cannabis dispensaries.
Additional Shroom Products:
Edibles | Food products like gummies and chocolates that contain psilocybin. The dosage is made simple as the manufacturers specify the amount per serving. |
Capsules | Tasteless and easily integrated into your wellness routine. They contain small dosages for a gentle enhancement of your routine. |
Beverages | Similar to edibles but in a drinkable form. They come in a variety of options like chocolate, coffee, or tea. |
How to Determine Your Dose at Magic Mushroom Dispensaries
Although magic mushrooms aren’t typically used to treat depression, Canada has taken a progressive step. They’ve approved the testing and medical use of psilocybin, a Schedule I substance under the Controlled Drugs and Substances Act, for certain patients suffering from severe major depressive disorder. This could potentially benefit tens of thousands exploring alternative treatments for anxiety and depression through clinical trials.
Commonly Asked Questions
Can psilocybin be purchased from a What does a medicinal mushroom dispensary sell?
A medicinal mushroom dispensary usually offers products such as Reishi, Turkey Tail, and Lion’s Mane. If you’re curious about the mushroom realm, an online magic mushroom dispensary may be your ideal destination. They specialize in a range of mushroom products, including dried mushrooms and other psychedelic substances.
Is a 25 mg dose effective for depression treatment?
Research into the optimal psilocybin dosages for depression treatment is still ongoing. Some studies have concentrated on lower dosages, whereas others have examined higher psilocybin quantities. One possible approach could be to start with a microdose and gradually increase the dosage.
Can shrooms be bought in Toronto?
Online mushroom sellers allow you to shop from anywhere in Canada. Regardless of your province or city, these online platforms ensure delivery right to your doorstep.
What is the most economical product in an online mushroom store?
Dried mushrooms are typically the preferred choice for customers due to the various quantities available. The price may fluctuate depending on whether you require a small quantity like 1 gram or want to purchase in bulk. While edibles and other products are reasonably priced, they might not be as cost-effective as dried mushrooms.
Can a single shroom dose help alleviate depression?
Some research indicates that a single dose might be enough to diminish depression symptoms. However, it’s important to remember that study participants also engaged in talk therapy along with the treatment. The combination of psychedelic therapy and therapeutic sessions appears to yield the most effective results.
About the Author
This article was crafted by Charles L. Raison et al.; Jeremy D. Coplan, MD and Dorothy P. Reddy, MD; Albert Garcia-Romeu, Frederick S Barrett, Theresa M Carbonaro, Matthew W Johnson, and Roland R Griffiths; Vince Polito
Richard J. Stevenson, Rebecca Smausz, Joanna Neill, and John Gigg are also contributors.
Affiliated Organizations:
- Usona Institute, Fitchburg, Wisconsin
- SUNY Downstate Medical Center, Brooklyn, New York
- Neurogenesis Clinics, Brooklyn, New York
- The Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
- Center for Psychedelic and Consciousness Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA
- Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA
- Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
- Department of Cognitive Science, Macquarie University, Sydney, Australia
- Department of Psychology, Macquarie University, Sydney, Australia
- Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, UK
- Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester, UK
- Medical Psychedelics Working Group, Drug Science, UK